In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites. (December 2021)

• Record Type: Journal Article
• Authors: Daneshmand, Ali; Young, Petrina; Campbell, Bronwyn; Kheravii, Sarbast K.; Sharma, Nishchal K.; Afshari, Roya; Dias, Daniel A.; Flavel, Matthew; Kitchen, Barry; Wu, Shu-Biao
• Is Part Of: International journal for parasitology. Volume 17(2021)
• Page Start: 1
• Page End: 4
• Publication Date: 2021-12
• Subjects: Sugarcane extract -- Avian coccidiosis -- Sporozoites -- In vitro excystation -- Anticoccidial agents -- Eimeria species; Parasitic diseases -- Chemotherapy -- Periodicals; Drug resistance -- Periodicals; 616.96061
• DOI: 10.1016/j.ijpddr.2021.07.001
• Languages: English
• ISSNs: 2211-3207

Abstract

Abstract: The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain™. All treatments were incubated in RPMI media containing live sporozoites at 37 °C for 14 h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain™ decreased (P < 0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P > 0.05). In conclusion, Polygain™ could be a potential candidate as an anticoccidial agent. Graphical abstract: Image 1