The EurValve model execution environment. Issue 1 (6th February 2021)

• Record Type: Journal Article
• Authors: Bubak, M.; Czechowicz, K.; Gubała, T.; Hose, D. R.; Kasztelnik, M.; Malawski, M.; Meizner, J.; Nowakowski, P.; Wood, S.
• Is Part Of: Interface focus. Volume 11:Issue 1(2021)
• Publication Date: 2021-02-06
• Subjects: personalized medicine -- medical IT -- decision support systems; Physical sciences -- Periodicals; Life sciences -- Periodicals; 500
• DOI: 10.1098/rsfs.2020.0006
• Languages: English
• ISSNs: 2042-8898

Abstract

Abstract : The goal of this paper is to present a dedicated high-performance computing (HPC) infrastructure which is used in the development of a so-called reduced-order model (ROM) for simulating the outcomes of interventional procedures which are contemplated in the treatment of valvular heart conditions. Following a brief introduction to the problem, the paper presents the design of a model execution environment, in which representative cases can be simulated and the parameters of the ROM fine-tuned to enable subsequent deployment of a decision support system without further need for HPC. The presentation of the system is followed by information concerning its use in processing specific patient cases in the context of the EurValve international collaboration.