Recurrent pulmonary cryptococcosis during chronic HBV infection: A case report. Issue 50 (17th December 2021)

• Record Type: Journal Article
• Authors: Liu, Huan; Shen, Shu; Wang, Qiuhui
• Editors: Saranathan., Maya
• Is Part Of: Medicine. Volume 100:Issue 50(2021)
• Page Start: e28250
• Publication Date: 2021-12-17
• Subjects: hepatitis B virus -- opportunistic infection -- pulmonary cryptococcosis -- recurrence; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000028250
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Pulmonary cryptococcosis is one of the important opportunistic infections and has a wide range of symptoms depending on the underlying conditions. Here, we reported a case living with chronic hepatitis B virus infection who had a recurrent pulmonary cryptococcosis. Patient concerns: A 51-year-old male patient was admitted to our center because of cough, fatigue, and shortness of breath for 2 weeks. Diagnosis: Pulmonary infection was suggested by chest computed tomography. Most lab examinations for infection were negative and only cryptococcal antigen testing was positive. Therefore, a clinical diagnosis of pulmonary cryptococcosis was made. Interventions: Fluconazole (200 mg/day) and bicyclol (50 mg/day) was given orally. Outcomes: During the follow-up of 3 and 6 months, his conditions improved, and he recovered fully. Moreover, cryptococcal antigen level was 12.57 ng/mL. During the 2-year follow-up, no recurrence occurred. Lessons: This case highlights the importance of the awareness of opportunistic infections during chronic hepatitis B virus infection, especially the potential of recurrence.