Teaching NeuroImage: Bilateral Nucleus Tractus Solitarius Lesions in Neurogenic Respiratory Failure. (4th January 2022)

• Record Type: Journal Article
• Authors: Parayil Sankaran, Bindu; Wortman, Saskia B.; Willemsen, Michel A.; Balasubramaniam, Shanti
• Is Part Of: Neurology. Volume 98:Number 1(2022)
• Page Start: e103
• Page End: e104
• Publication Date: 2022-01-04
• Subjects: Neurology -- Periodicals; Neurology -- Periodicals; Neurologie -- Périodiques; 616.8
• DOI: 10.1212/WNL.0000000000012614
• Languages: English
• ISSNs: 0028-3878

Abstract

Abstract : A 7-year-old girl with MEGD(H)EL [3-methylglutaconic aciduria, dystonia-deafness, (hepatopathy), encephalopathy, Leigh-like syndrome, SERAC1] 1 presented with worsening respiratory compromise. The evaluation showed type II respiratory failure (e.g., hypercapnic) necessitating mechanical ventilation. Cerebral MRI demonstrated progression of known changes in MEGD(H)EL (Figure, A and B) and symmetric nucleus tractus solitarius (NTS) involvement (Figure, C and D). She was ventilator dependent and subsequently died from the effect of the disease.