Favorable colorectal cancer mortality-to-incidence ratios in countries with high expenditures on health and development index: A study based on GLOBOCAN database. Issue 41 (15th October 2021)

• Record Type: Journal Article
• Authors: Wang, Chi-Chih; Sung, Wen-Wei; Yan, Pei-Yi; Ko, Po-Yun; Tsai, Ming-Chang
• Other Names: Derakhshan. Mohammad section editor.
• Is Part Of: Medicine. Volume 100:Issue 41(2021)
• Publication Date: 2021-10-15
• Subjects: colorectal cancer -- expenditure -- incidence -- mortality -- mortality-to-incidence ratio; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000027414
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Global variation in the incidence and outcomes of colorectal cancer (CRC) is associated with many factors, among which screening policies and early treatment play substantial roles. However, screening programs and intense treatment are expensive and require good health care systems. For CRC, no clear association has yet been established between clinical outcomes and health care disparities. Method: We used the mortality-to-incidence ratio (MIR) of CRC as a measure of clinical outcomes for comparison with the Human Development Index (HDI), current health expenditure (CHE), and current health expenditure as a percentage of gross domestic product (CHE/GDP) using linear regression analyses. We included 171 countries based on data from the GLOBOCAN 2018 database. Results: We found that the regions with the lowest MIRs for CRC are Oceania and North America. A significant correlation was observed between incidence, mortality and HDI, CHE, and CHE/GDP among the countries enrolled. Furthermore, lower MIRs of CRC significantly correlated with higher HDI, CHE, and CHE/GDP ( P < 0.001, P < 0.001, and P < 0.001, respectively). Conclusion: : CRC MIRs tend to be most favorable in countries with high health care expenditures and a high HDI. Abstract : Supplemental Digital Content is available in the text