The Batman and Robin of liver-stage immunity to malaria. Issue 1 (January 2022)

• Record Type: Journal Article
• Authors: Heath, William R.; Holz, Lauren E.; Fernandez-Ruiz, Daniel
• Is Part Of: Trends in parasitology. Volume 38:Issue 1(2022)
• Page Start: 7
• Page End: 8
• Publication Date: 2022-01
• Subjects: malaria -- liver -- CD8 T cells -- memory -- vaccines; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2021.11.002
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract : Malaria parasites replicate within the liver shortly after infection. This stage can be controlled by CD8 T cells, but which subsets undertake this function is unclear. Lefebvre et al . now elegantly show that effector memory T (TEM ) cells are avid participants, working as a dynamic duo with liver tissue-resident memory T (TRM ) cells to combat infection.