New curative approach using embolization followed by moderate-dose radiotherapy after surgical failure for large right heart metastasis. (January 2022)

• Record Type: Journal Article
• Authors: Delanian, Sylvie; Awad, Sameh; de Gramont, Aimery
• Is Part Of: Clinical and translational radiation oncology. Volume 32(2022)
• Page Start: 1
• Page End: 5
• Publication Date: 2022-01
• Subjects: Cardiac metastasis -- Radiotherapy -- Transcatheter arterial embolization -- Cardiac imaging; Cancer -- Radiotherapy -- Periodicals; Oncology -- Periodicals; Cancer -- Radiotherapy; Oncology; Radiation Oncology; Neoplasms -- radiotherapy; Translational Medical Research; Periodicals; Electronic journals; Periodicals; 616.9940642
• DOI: 10.1016/j.ctro.2021.10.004
• Languages: English
• ISSNs: 2405-6308

Abstract

Highlights: Rapid improvement observed in a patient with a large cardiac metastasis. There is today no curative therapeutic option when the tumor is inoperable. Transcoronary tumor embolization plus moderate targeted radiotherapy should be a new option for tumor control. Abstract: Purpose: Cardiac metastasis is a rare fatal event. An intracavitary right tumor mainly in the ventricle is difficult to manage. Literature reports suggest that cardiac surgery in oligometastatic patients could offer median survival of 1 year. We investigated salvage treatment comprising transcoronary tumor embolization followed 15 days later by cardiac radiotherapy (40.5 Gy/15 fractions). Cases: We report two cases of severe right cardiac metastasis with a history of abdominal cancer managed by this salvage treatment following residual cardiac mass after previous cardiac surgery. Conclusion: Both symptomatic patients improved progressively and were locally controlled for at least 1 year without toxicity.