Bioinspired artificial platelets for transfusion applications in traumatic hemorrhage. Issue 2 (18th October 2019)

• Record Type: Journal Article
• Authors: Girish, Aditya; Sekhon, Ujjal; Sen Gupta, Anirban
• Is Part Of: Transfusion. Volume 60:Issue 2(2020)
• Page Start: 229
• Page End: 231
• Publication Date: 2019-10-18
• Subjects: Hematology -- Periodicals; Blood -- Transfusion -- Periodicals; Blood Group Antigens -- Periodicals; Blood Preservation -- Periodicals; Blood Transfusion -- Periodicals; 615
• DOI: 10.1111/trf.15543
• Languages: English
• ISSNs: 0041-1132

Abstract

KEY IDEAS: Among blood components, platelets (PLTs) present the toughest logistic challenges in transfusion due to limited availability, difficult portability and storage, high contamination risks, and very short shelf life (approx. 5 days). Robust research efforts are being directed to develop biologic PLTs in vitro as well as design biosynthetic and artificial PLT technologies that can potentially resolve these challenges to allow adequate availability and timely transfusion to improve survival in trauma.