Self‐photocatalyzed Homolytic Dehalogenative Alkylation/Cyclization of Unactivated Alkenes Based on the Quinazolinone Skeleton via Energy Transfer. Issue 12 (27th October 2021)

• Record Type: Journal Article
• Authors: Sun, Bin; Tang, Xiaoli; Shi, Rongcheng; Yan, Zhiyang; Li, Bingqian; Tang, Chen; Jin, Can; Wu, Chunlei L.; Shen, Runpu P.
• Is Part Of: Asian journal of organic chemistry. Volume 10:Issue 12(2021)
• Page Start: 3390
• Page End: 3395
• Publication Date: 2021-10-27
• Subjects: Alkylation/cyclization -- Energy transfer -- Malonate -- Quinazolinone -- Self-photocatalyzsis; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202100606
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: A mild, external photocatalyst‐ and additive‐free protocol for photo‐induced alkylation/cyclization of unactivated alkenes with halides has been developed. This strategy showed excellent regioselectivity and simple operation to synthesize alkyl‐substituted quinazolinones with a broad substrate scope. More importantly, chlorinated alkanes were also compatible with this transformation. Abstract : A mild, external photocatalyst and additive‐free protocol for photo‐induced alkylation/cyclization of unactivated alkenes with halides has been developed.