Multigenerational effects modify the tolerance of mosquito larvae to chlorpyrifos but not to a heat spike and do not change their synergism. (1st January 2022)

• Record Type: Journal Article
• Authors: Meng, Shandong; Delnat, Vienna; Stoks, Robby
• Is Part Of: Environmental pollution. Volume 292:Part A(2022)
• Publication Date: 2022-01-01
• Subjects: Global change -- Multigenerational effects -- Multiple stressors -- Synergistic interaction -- Temperature extremes; Pollution -- Periodicals; Pollution -- Environmental aspects -- Periodicals; Environmental Pollution -- Periodicals; Pollution -- Périodiques; Pollution -- Aspect de l'environnement -- Périodiques; Pollution -- Effets physiologiques -- Périodiques; Pollution; Pollution -- Environmental aspects; Periodicals; Electronic journals; 363.73
• DOI: 10.1016/j.envpol.2021.118333
• Languages: English
• ISSNs: 0269-7491

Abstract

Abstract: While interactions with global warming and multigenerational effects are considered crucial to improve risk assessment of pesticides, these have rarely been studied in an integrated way. While heat extremes can magnify pesticide toxicity, no studies tested how their combined effects may transmit to the next generation. We exposed mosquito larvae in a full factorial, two-generation experiment to a heat spike followed by chlorpyrifos exposure. As expected, the heat spike magnified the chlorpyrifos-induced lethal and sublethal effects within both generations. Only when preceded by the heat spike, chlorpyrifos increased mortality and reduced the population growth rate. Moreover, chlorpyrifos-induced reductions in heat tolerance (CTmax), acetylcholinesterase (AChE) activity and development time were further magnified by the heat spike. Notably, when parents were exposed to chlorpyrifos, the chlorpyrifos-induced lethal and sublethal effects in the offspring were smaller, indicating increased tolerance to chlorpyrifos. In contrast, there was no such multigenerational effect for the heat spike. Despite the adaptive multigenerational effect to the pesticide, the synergism with the heat spike was still present in the offspring generation. Generally, our results provide important evidence that short exposure to pulse-like global change stressors can strongly affect organisms within and across generations, and highlight the importance of considering multigenerational effects in risk assessment. Graphical abstract: Image 1 Highlights: The heat spike increased the lethal and sublethal effects of chlorpyrifos. Offspring was more tolerant when parents were also exposed to chlorpyrifos. Multigenerational effects did not change how offspring dealt with the heat spike. Synergism between heat spike and chlorpyrifos did not differ between generations. Exposure to pulse stressors strongly affect organisms within and across generations. Abstract : Capsule: Multigenerational effects modify the tolerance of mosquito larvae to a pesticide but do not change the synergism with a heat spike.