Fast Detection of Entacapone by a Lanthanide–Organic Framework with Rhombic Channels. Issue 69 (22nd October 2021)

• Record Type: Journal Article
• Authors: Min, Hui; Wu, Shuangyan; Han, Zongsu; Chen, Zhonghang; Sun, Tiankai; Shi, Wei; Cheng, Peng
• Is Part Of: Chemistry. Volume 27:Issue 69(2021)
• Page Start: 17459
• Page End: 17464
• Publication Date: 2021-10-22
• Subjects: 1H-1, 2, 3-triazole-4, 5-dicarboxylic acid -- Entacapone -- internal filtration effect -- lanthanide-organic framework -- photoinduced electron transfer; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202103297
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Entacapone (ENT) is a powerful catechol‐ O ‐methyl transferase inhibitor that is used for the diagnosis and treatment of Parkinson's syndrome, but the amount used must be well controlled to avoid overtreatment and side effect. Fast and selective detection of ENT needs well‐matched energy levels and well‐designed sensor‐ENT interaction which is highly challenging. In this work, a water stable europium‐based metal‐organic framework (Eu‐TDA ) was synthesized to detect ENT by luminescence with excellent reusability and selectivity in the presence of main coexisting and interference species of plasma with a limit of detection of 5.01 μM. The experimental results showed that the luminescence of Eu‐TDA can be effectively quenched by ENT via well‐designed photoinduced electron transfer mechanism and internal filtration effect mechanism in the system. Abstract : A lanthanide‐organic framework was synthesized to detect entacapone by luminescence with excellent reusability and selectivity via well‐designed photoinduced electron transfer mechanism and internal filtration effect.