RiGOR: a prospective observational study comparing the effectiveness of treatment strategies for open-angle glaucoma. (January 2016)

• Record Type: Journal Article
• Authors: Coleman, Anne L; Lum, Flora C; Velentgas, Priscilla; Campion, Daniel; Su, Zhaohui; Gliklich, Richard E
• Is Part Of: Journal of comparative effectiveness research. Volume 5:Number 1(2016)
• Page Start: 65
• Page End: 78
• Publication Date: 2016-01
• Subjects: comparative effectiveness -- disparities -- glaucoma medication -- glaucoma surgery -- open-angle glaucoma -- registry; Medical care -- Research -- Periodicals; Medical care -- Research -- Evaluation -- Periodicals; Medical care -- Decision making -- Periodicals; Evidence-based medicine -- Periodicals; Medicine, Comparative -- Periodicals; 362.1072
• DOI: 10.2217/cer.15.56
• Languages: English
• ISSNs: 2042-6305

Abstract

Aims: The RigOR study was designed to assess comparative effectiveness of medications, laser trabeculoplasty and incisional surgery in patients with open-angle glaucoma (OAG) in the community initiating a new or additional course of therapy as judged necessary by their ophthalmologist. This paper focuses specifically on demographic and clinical characteristics of OAG patients at enrollment.Patients & methods: A total of 2597 with OAG already on medical therapy were enrolled from 45 community and academic practices throughout the USA.Results: Overall, 784 (30%) patients were treated with laser surgery, 436 with other surgical procedures (17%), and 1377 with additional medication (53%). Patients had mild (35%) or moderate (31%) glaucoma, with 28% with severe glaucoma.Conclusion: The RiGOR study enrolled a diverse population and will provide valuable information regarding visual function and treatment patterns among different racial/ethnic populations. African–American and Hispanic patients entered the study with poorer visual acuity and more severe glaucoma.