SAT0157 The prevalence of dyslipidemia and daily nutritional intake in rheumatoid arthritis patients: a study of the korean national health and nutrition examination survey (KNHANES). (12th June 2018)

• Record Type: Journal Article
• Authors: Joo, S. H.; Song, Y. W.
• Is Part Of: Annals of the rheumatic diseases. Volume 77(2018)Supplement 2
• Page Start: 939
• Page End: 940
• Publication Date: 2018-06-12
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2018-eular.6695
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Lipid metabolism appear to be changed in rheumatoid arthritis (RA) patients because of disease activity and inflammation. Objectives: It was not clear in the previous studies that lipid profiles status is associated with nutritional intake in RA patients. Methods: We analyzed RA, dyslipidemia, serum lipid profiles (total cholesterol, TG, HDL, and LDL) and nutritional intake data related lipid from the data of KNHANES (N=22, 948, estimated population size=48, 402, 221). We analyzed the prevalence of RA and abnormal status of lipid profiles using general linear model and logistic regression with complex sample design method adjusted by age and sex and evaluated the association between RA and dyslipidemia including nutritional intake data. Results: The prevalence of RA was 1.21% [95% CI: 1.07–1.38]. The prevalence of dyslipidemia with RA (3.31% [95% CI: 2.63–4.17]) was significantly increased compared with that of dyslipidemia without RA (1.37% [95% CI: 1.17–1.59], p<0.001). LDL (RA vs. control: 117.77±3.87 mg/dL vs. 114.47±0.51 mg/dL, p<0.001) was significantly increased, whereas TG (RA vs. control: 129.21±6.38 mg/dL vs. 136.72±1.20 mg/dL, p<0.001) was significantly decreased in RA. Total cholesterol tended to be higher in RA (RA vs. control: 198.12±3.09 mg/dL vs. 188.11±0.39 mg/dL, p=0.051). but HDL (RA vs. control: 54.16±1.42 mg/dL vs. 52.46±0.15 mg/dL, p=0.98) was not different between two groups. There were no differences in nutritional intake volume including total diet volume, energy intake, water, carbohydrate, protein, fat, other fatty acids and dietary fiber (Table). Conclusions: We showed increased prevalence of dyslipidemia patients in the individuals with RA than those without RA. Serum LDL levels was increased and TG was decreased in RA patients of the Korean population survey. Disclosure of Interest: None declared