Sentinel lymph node biopsy and axillary dissection in breast cancer: results in a Latina population. (October 2015)

• Record Type: Journal Article
• Authors: Dunstan, Jorge; Castañeda, Carlos; Abugattas, Julio; Cotrina, Jose; Castillo, Miluska; Villegas, Valeria; Dolores-Cerna, Ketty; Belmar-Lopez, Carolina; Guerra, Henry; Gomez, Henry; Vidaurre, Tatiana
• Is Part Of: Breast cancer management. Volume 4:Number 6(2015)
• Page Start: 295
• Page End: 302
• Publication Date: 2015-10
• Subjects: axillary -- breast -- dissection -- Instituto Nacional de Enfermedades Neoplasicas -- Latinas -- recurrence -- sentinel; Breast -- Cancer -- Periodicals; Breast -- Cancer -- Treatment -- Periodicals; 616.9944905
• DOI: 10.2217/bmt.15.26
• Languages: English
• ISSNs: 1758-1923

Abstract

Aim: we aim to evaluate accuracy of sentinel node (SN) in biopsy breast cancer (BC).Patients & methods: We reviewed 1259 early cases who underwent SN biopsy between 1996 and 2010.Results: Median age was 52 years; and 48.9, 39.7, 68.4 and 12.1% had T2, HG-III, ER + and HER2 +++, respectively. Median SN was two nodes, 34.3% had SN + and 41.6% went to axillary dissection (AD). SN-positive is associated with AD-positive nodes (p < 0.001). Number of SN-positive were related to number of AD-positive nodes (p < 0.001). Factors predicting AD-positive nodes in the SN-positive group were lymphovascular invasion (p = 0.016) and HG III (p = 0.041). Axillary recurrence was similar in those with or without AD nodes (0.0136 vs 0.0153, p = 0.8023).Conclusion: The SN predicts AD involvement and offers a low rate of axillary recurrence in our Latina population.