Disseminated cryptococcosis in HIV negative patient. (12th May 2018)

• Record Type: Journal Article
• Authors: Hassoun, Ali; Mehrotra, Neha
• Is Part Of: BMJ case reports. Volume 2018
• Publication Date: 2018-05-12
• Subjects: eye -- meningitis; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2017-223500
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 52-year-old white diabetic male with 4-weeks history of persistent cough followed by headache, drenching night sweats, low-grade fever, worsening photophobia, nausea and vomiting was presented. Examination was significant for photophobia and diminution of vision. His spinal fluid and blood cultures were positive for Cryptococcus neoformans . Intravenous fluconazole were given for 2 weeks followed by oral fluconazole. There was significant improvement in systemic and ocular symptoms. HIV serology was negative, but his CD4 counts were low with inverted CD4:CD8 ratio.