Pemphigoid gestationis successfully treated with intravenous immunoglobulin. (7th April 2018)

• Record Type: Journal Article
• Authors: Almeida, Filipa Tavares; Sarabando, Rita; Pardal, Joana; Brito, Celeste
• Is Part Of: BMJ case reports. Volume 2018
• Publication Date: 2018-04-07
• Subjects: dermatology -- obstetrics, gynaecology and fertility -- obstetrics and gynaecology; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2018-224346
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Pemphigoid gestationis (PG), also known as herpes gestationis, is a rare autoimmune blistering disease specific to pregnancy, which usually presents in the second or third trimesters and, in 15%–25% of cases, during the immediate postpartum period. 1 Although the ethiopathogeny of PG is not fully clarified, most patients develop antibodies against a 180 kDa transmembrane hemidesmosomal protein (BP180; BPAG2; collagen XVII). 2 PG has a strong association with human leucocyte antigens DR3 and DR4. 3 We report a case of a 29-year-old female patient with PG successfully treated with intravenous immunoglobulin.