Bilateral 'vitelliform-like' macular lesions in a patient with multiple myeloma. (23rd November 2010)

• Record Type: Journal Article
• Authors: Khan, Javeed M; McBain, Vikki; Santiago, Cynthia; Lois, Noemi
• Is Part Of: BMJ case reports. Volume 2010
• Publication Date: 2010-11-23
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr.05.2010.3049
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 73-year-old woman was referred to the eye clinic in February 2005 with reduced vision in both eyes. On examination, her visual acuity was 20/40, N6 right eye and 20/64, N6 left eye. Bilateral unusual 'vitelliform-like' lesions at the macula (accumulation of yellow material in the subretinal space), which demonstrated blocked fluorescence on fluorescein angiography and a lack of increased autofluorescence signal on fundus autofluorescence imaging, were detected. The patient was followed-up until April 2007 when retinal haemorrhages were detected and blood work-up was undertaken; during this follow-up period the material present at the macula progressively disappeared. As a result of the blood work-up, the diagnosis of multiple myeloma was established; the macular lesions were thought to relate to the latter disease and represent subretinal deposition of immunoglobulin.