Dulaglutide-induced cerebral venous thrombosis in a patient with type 2 diabetes mellitus. (8th November 2018)

• Record Type: Journal Article
• Authors: Rajput, Rajesh; Pathak, Vaibhav; Yadav, Pawan Kumar; Mishra, Sanat
• Is Part Of: BMJ case reports. Volume 2018
• Publication Date: 2018-11-08
• Subjects: diabetes -- stroke; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2018-226346
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Though patients with diabetes mellitus are at a high risk of atherothrombotic events, every such event should not be attributed to the disease itself. We present a case of a patient with diabetes with headache and blurring of vision for 3 days. Brain imaging revealed right transverse sinus thrombosis and acute infarct of the right posterior parieto-occipital region, predominantly in the posterior cortical watershed zone. The patient was on subcutaneous dulaglutide for 3 weeks and was having nausea and vomiting. Various causes of cerebral venous thrombosis were ruled out with appropriate laboratory investigations. Finally, cerebral venous thrombosis was attributed to dulaglutide-induced nausea and vomiting which led to severe dehydration.