Chest wall and rib irradiation and toxicities of early-stage lung cancer patients treated with CyberKnife stereotactic body radiotherapy. (December 2014)

• Record Type: Journal Article
• Authors: Podder, Tarun; Biswas, Tithi; Yao, Min; Zhang, Yuxia; Kim, Ellen; Ellis, Rodney J; Lo, Simon S; Machtay, Mitchell
• Is Part Of: Future oncology. Volume 10:Number 15(2014)
• Page Start: 2311
• Page End: 2317
• Publication Date: 2014-12
• Subjects: chest pain -- chest wall toxicity -- CyberKnife -- rib fracture -- stereotactic body radiotherapy; Oncology -- Periodicals; 616.99405
• DOI: 10.2217/fon.14.158
• Languages: English
• ISSNs: 1479-6694

Abstract

ABSTRACT : Aim: The aim of the study is to evaluate the chest wall and rib toxicities in primary lung cancer patients treated with CyberKnife-based stereotactic body radiotherapy.Materials & methods: In this study, data were collected from the 118 patients, of which 25 patients who had longer follow-up (mean: 21.9 months) were considered. Studied parameters were maximum point dose, doses to 1–100 cm 3 of chest wall and 1–10 cm 3 of ribs.Results: Three patients developed chest wall pain (grade I). 25 studied patients, on average, received 27.7 Gy to 30 cm 3 of chest wall and 50.4 Gy to 1 cm 3 of rib. Nine patients had more than 30 Gy dose to 30 cm 3 of chest wall. No rib bone fracture was found.Conclusion: No correlations of chest wall pain and volume of irradiation were found.