AB0555 POTENTIAL ROLE OF PAROTID ELASTOGRAPHY IN DIAGNOSIS AND CLASSIFICATION OF PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME. (June 2019)

• Record Type: Journal Article
• Authors: Satış, Hasan; Demir, Betül Nur; Salman, Reyhan Bilici; Temel, Esra; Babaoglu, Hakan; Atas, Nuh; Güler, Aslıhan Avanoglu; Karadeniz, Hazan; Cingil, Emetullah; Tufan, Abdurrahman; Ozturk, Mehmet Akif; Haznedaroglu, Seminur; Göker, Berna
• Is Part Of: Annals of the rheumatic diseases. Volume 78(2019)Supplement 2
• Page Start: 1740
• Page End: 1740
• Publication Date: 2019-06
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2019-eular.6036
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Despite the improvements in classifying patients with primary Sjögren's syndrome with usage of the new 2016 ACR/EULAR classification criteria, there remains to be a need for improvement and investigating the value of new modalities in diagnosing as well as classifiying these patients. Objectives: to investigate potential role of parotid elastography in diagnosis and classification of patients with primary Sjögren's syndrome (pSs) Methods: This is a cross sectional analysis of patients with primary Sjögren's syndrome followed up in our out-patient Rheumatology clinic. We performed chart reviews and retrospectively investigated the available data on files to search whether or not our clinically diagnosed patients satisfied the 2002 AEG and/or 2016 ACR/EULAR criteria sets. Ultrasonographic and elastographic evaluation of parotid and submandibular glands bilaterally were performed on consecutive patients with clinical diagnosis of pSs and contributions of these findings to classification criteria sets were interpereted Results: There were 95 pSs patients and 30 healthy gender and age matched controls. Strain ratio, shearwave velocity and Pascal values of the glands were examined. Parotid strain ratio, submandibular velocity and submandibular pascal values were statistically significantly different compared to healthy controls (Table).%86 of patients considered clinically as Sjögren syndrome satisfied 2016 ACR/EULAR (criteria patients) and%84 satisfied 2002 AER classification criteria. We grouped patients with respect to parotid strain ratio taking 1.0875 as the cut-off value. Those patients who did not satisfy 2016 ACR/EULAR criteria, but clinically diagnosed as pSs (non criteria pSs patients), also had significantly higher parotid strain ratio and submandibular velocity compared to healthy controls (p:0, 016 and p<0, 001 respectively). Interestingly, both criteria and non-criteria pSs patients had similar parotid strain ratio and submandibular velocity value (p:0, 892 and p:0, 260, respecitively) Conclusion: Parotid shear elastography is an easy and nonivasive method and can be a useful tool for the diagnosis and classification of patients with pSs (1). References: [1] Mossel E, Delli K, van Nimwegen JF, Stel AJ, Kroese FGM, Spijkervet FKL, Vissink A, Arends S, Bootsma H; EULAR US-pSS Study Group. Ultrasonography of major salivary glands compared with parotid and labial gland biopsy and classification criteria in patients with clinically suspected primary Sjögren's syndrome Ann Rheum Dis. 2017 Nov;76(11):1883-1889. doi: 10.1136/annrheumdis-2017-211250 Disclosure of Interests: None declared