AB0853 BONE DENSITOMETRY IN CROHN'S DISEASE: RISK FACTORS FOR OSTEOPENIA AND OSTEOPOROSIS. (June 2019)

• Record Type: Journal Article
• Authors: Soua, Sabrine; Issaoui, Dhilel; Kchir, Hela; Trad, Nouha; Chaabouni, Hatem; Maamouri, Nadia
• Is Part Of: Annals of the rheumatic diseases. Volume 78(2019)Supplement 2
• Page Start: 1894
• Page End: 1895
• Publication Date: 2019-06
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2019-eular.7994
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Osteoporosis and osteopenia are common situations in chronic inflammatory bowel disease (IBD), particularly in crohn's disease. Objectives: The objective of our study was to determine the prevalence of these affections during crohn's disease and to identify the risk factors for osteopenia and osteoporosis. Methods: We conducted a descriptive monocentric retrospective study of consecutive patients with crohn's disease who were hospitalized between January 2016 and December 2018. Results: We included 100 patients (64 female and 36 male) with an average age of 37 years [17-68 years]. Among these patients 21% were smokers and among women 20% were in menopause. Bone densitometry was performed in 39 patients. It was found to be pathological in 53.8% of cases. The rate of osteoporosis was 17.9% (7 patients) and the rate of osteopenia was 35.9% (14 patients). Tobacco and a BMI of less than 18 had a statistically significant association with osteopenia (p=0.046; p=0.038 respectively). The presence of a family history of IBD had a statistically significant influence on a pathological bone densitometric investigation (p=0.036). An albuminemia rate of less than 35g/dl had an association at the limit of significance with bone pathology in BMD (p=0.059). Conclusion: Osteoporosis and osteopenia are frequent during crohn's disease. They are in the majority of cases asymptomatic. This makes bone densitometry essential, especially in the presence of a family history of IBD, smoking and malnutrition (BMI less than 18) in order to act early and avoid complications such as fractures. Disclosure of Interests: None declared