X-ray grating interferometry design for the 4D GRAPH-X system. (25th October 2021)

• Record Type: Journal Article
• Authors: Patera, Alessandra; Arboleda, Carolina; Ferrero, Veronica; Fiorina, Elisa; Jefimovs, Konstantins; Giudice, Alessandro Lo; Milian, Felix Mas; Mereu, Paolo; Pallotta, Stefania; Ramello, Luciano; Re, Alessandro; Visca, Lorenzo; Cerello, Piergiorgio
• Is Part Of: Journal of physics. Volume 55:Number 4(2022)
• Publication Date: 2021-10-25
• Subjects: x-ray phase contrast imaging -- talbot-lau grating interferometer -- dynamic imaging -- wavefront simulation; Physics -- Periodicals; 530
• DOI: 10.1088/1361-6463/ac2fd6
• Languages: English
• ISSNs: 0022-3727

Abstract

Abstract: The 4D GRAPH-X (Dynamic GRAting-based PHase contrast x-ray imaging) project aims at developing a prototype of an x-ray grating-based phase-contrast imaging scanner in a laboratory setting, which is based on the Moirè single-shot acquisition method in order to be optimized for analysing moving objects (in the specific case, a dynamic thorax phantom), that could evolve into a suitable tool for biomedical applications although it can be extended to other application fields. When designing an x-ray Talbot-Lau interferometer, high visibility and sensitivity are two important figures of merit, strictly related to the performance of the system in obtaining high quality phase contrast and dark-field images. Wave field simulations are performed to optimize the setup specifications and construct a high-resolution and high-sensitivity imaging system. In this work, the design of a dynamic imaging setup using a conventional milli-focus x-ray source is presented. Optimization by wave front simulations leads to a symmetric configuration with 5.25 μ m pitch at third Talbot order and 45 keV design energy. The simulated visibility is about 22%. Results from GATE based Monte Carlo simulations show a 19% transmission percentage of the incoming beam into the detector after passing through all the gratings and the sample. Such results are promising in view of building a system optimized for dynamic imaging.