Changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops. Issue 6 (December 2021)
- Record Type:
- Journal Article
- Title:
- Changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops. Issue 6 (December 2021)
- Main Title:
- Changes in visual quality with soft contact lenses after the instillation of hyaluronic acid eye drops
- Authors:
- Carpena-Torres, Carlos
Pastrana, Cristina
Rodríguez-Pomar, Candela
Serramito, María
Batres, Laura
Carracedo, Gonzalo - Abstract:
- Highlights: During Ocufilcon D contact lens wear, the instillation of 0.1% and 0.2% hyaluronic acid showed an improvement in the visual quality. During Somofilcon A contact lens wear, the instillation of 0.3% hyaluronic acid showed a deterioration in the visual quality. Depending on the properties of contact lens materials, the instillation of hyaluronic acid could have a different effect on visual quality. Abstract: Purpose: To evaluate the changes in visual function and anterior surface aberrations during soft contact lens (SCL) wear after the instillation of hyaluronic acid (HA) eye drops with different viscosity. Methods: A prospective, randomized, and participant-masked study was performed. Twenty healthy participants (25.4 ± 2.6 years) were evaluated. Hydrogel (Ocufilcon D) and silicone-hydrogel (Somofilcon A) SCL were randomly assigned to both eyes of the same participant. Visual function in terms of high- and low-contrast corrected distance visual acuity (CDVA) and anterior contact lens surface aberrations (RMS HOA) were measured before and after the instillation, at different times, of different eye drops: saline (control) and 0.1%, 0.2%, and 0.3% HA. Results: Compared with the saline solution, during hydrogel SCL wear, there was an improvement (P < 0.05) in high-contrast CDVA after 3 and 10 min with 0.1% HA, and after 5 and 20 min with 0.2% HA. During silicone-hydrogel SCL wear, there was a deterioration (P < 0.05) in high-contrast CDVA after 1 and 30 min with 0.3%Highlights: During Ocufilcon D contact lens wear, the instillation of 0.1% and 0.2% hyaluronic acid showed an improvement in the visual quality. During Somofilcon A contact lens wear, the instillation of 0.3% hyaluronic acid showed a deterioration in the visual quality. Depending on the properties of contact lens materials, the instillation of hyaluronic acid could have a different effect on visual quality. Abstract: Purpose: To evaluate the changes in visual function and anterior surface aberrations during soft contact lens (SCL) wear after the instillation of hyaluronic acid (HA) eye drops with different viscosity. Methods: A prospective, randomized, and participant-masked study was performed. Twenty healthy participants (25.4 ± 2.6 years) were evaluated. Hydrogel (Ocufilcon D) and silicone-hydrogel (Somofilcon A) SCL were randomly assigned to both eyes of the same participant. Visual function in terms of high- and low-contrast corrected distance visual acuity (CDVA) and anterior contact lens surface aberrations (RMS HOA) were measured before and after the instillation, at different times, of different eye drops: saline (control) and 0.1%, 0.2%, and 0.3% HA. Results: Compared with the saline solution, during hydrogel SCL wear, there was an improvement (P < 0.05) in high-contrast CDVA after 3 and 10 min with 0.1% HA, and after 5 and 20 min with 0.2% HA. During silicone-hydrogel SCL wear, there was a deterioration (P < 0.05) in high-contrast CDVA after 1 and 30 min with 0.3% HA. Additionally, during silicone-hydrogel SCL wear, there was also a deterioration (P < 0.05) in low-contrast CDVA after 5 and 20 min with 0.3% HA. In terms of RMS HOA, there were no clinically relevant changes with both SCL. Conclusions: The instillation of HA eye drops could have a different effect on visual quality depending on their concentration of HA, the contact lens material, its surface ionicity, or other physicochemical properties that should be studied in future studies. … (more)
- Is Part Of:
- Contact lens & anterior eye. Volume 44:Issue 6(2021)
- Journal:
- Contact lens & anterior eye
- Issue:
- Volume 44:Issue 6(2021)
- Issue Display:
- Volume 44, Issue 6 (2021)
- Year:
- 2021
- Volume:
- 44
- Issue:
- 6
- Issue Sort Value:
- 2021-0044-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-12
- Subjects:
- Eye drops -- Visual quality -- Contact lens -- Hyaluronic acid
Anterior segment (Eye) -- Periodicals
Contact lenses -- Periodicals
Segment antérieur (Œil) -- Périodiques
Lentilles de contact -- Périodiques
617.752305 - Journal URLs:
- http://firstsearch.oclc.org/journal=1367-0484;screen=info;ECOIP ↗
http://www.sciencedirect.com/science/journal/13670484 ↗
http://www.contactlensjournal.com/ ↗
http://www.clinicalkey.com/dura/browse/journalIssue/13670484 ↗
http://www.clinicalkey.com.au/dura/browse/journalIssue/13670484 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.clae.2021.101471 ↗
- Languages:
- English
- ISSNs:
- 1367-0484
- Deposit Type:
- Legaldeposit
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- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3424.971000
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- 20087.xml