SAT0533 MRI ASSESSMENT OF HIP JOINTS INVOLVEMENT IN EARLY AXIAL SPONDYLOARTHRITIS PATIENTS. (June 2019)

• Record Type: Journal Article
• Authors: Agafonova, Ekaterina; Dubinina, Tatiana; Rumiantceva, Daria; Demina, Anastasiya; Erdes, Shandor
• Is Part Of: Annals of the rheumatic diseases. Volume 78(2019)Supplement 2
• Page Start: 1359
• Page End: 1359
• Publication Date: 2019-06
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2019-eular.3522
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Based on available data from epidemiological studies in Russia different degree of hip involvement was found in 46% of ankylosing spondylitis (AS) patients, but only 7% of all cases resulted in total hip replacement procedures. Objectives: To compare the ultrasound (US) manifestations of hip arthritis (coxitis) with the results of magnetic resonance imaging (MRI) of the hip joints (HJ) in patients with early axial spondyloarthritis (AxSpa). Methods: We examined 39 patients (mean age 28 ± 5.92 years) with a diagnosis of AxSpa (ASAS criteria 2009), with prescription inflammatory back pain no more than 5 years; age <45 years with US of coxitis. The median duration of the disease was 21 [3-60] months. BASDAI 4.0 ± 2.0, BASFI 2.0 [0.4; 3.5]. All patients underwent clinical, radiological, ultrasound, and MRI scans of HJ. For ultrasound coxitis was considered an increase in cervical-capsular distance (CCD) more than 7 mm. Coxitis is found in 27 men and 12 women. The CCD median was 7.5 [7.0; 8.2] mm. Results: All patients in addition to ultrasound signs of coxitis had MRI signs of inflammation of the HJ. Pain in the HJ was determined in 33 (85%) patients. The relationship between the level of pain and the amount of effusion in HJ was not detected. RCC significantly correlated with laboratory parameters of disease activity, such as ESR (r = 0.34) p <0.05 and CRP (r = 0.3), p <0.05. X-ray examination revealed radiological changes in 7 patients (BASRI hip II-III). The following inflammatory changes (IC) were identified in the study population using MRI: synovitis was established in 36 (92%) patients, bone marrow edema (BME) – in 1 (3%), and combination of synovitis with BME was observed in 2 patients (5%). Conclusion: Ultrasound allows you to detect changes in H in the early stages of the disease. It is possible to use ultrasound as a screening method to determine the presence of synovitis in the TBS. MRI HJ with AxSpa, allows to determine whether the patient has inflammatory changes, including in the absence of radiological changes in these joints. In 15% of cases, coxitis is asymptomatic at early stages, which requires a thorough examination of patients with AxSpa. In addition to clinical and radiological examination, all patients were subjected to MRI with T1 and STIR modes. Disclosure of Interests: Ekaterina Agafonova: None declared, Tatiana Dubinina: None declared, Daria Rumiantceva: None declared, Anastasiya Demina: None declared, Shandor Erdes Consultant for: Development of studies concepts., Speakers bureau: Educational meetings organized or supported by companies.