Development in SmI2 Catalyzed Reactions. Issue 37 (6th October 2021)

• Record Type: Journal Article
• Authors: Maity, Sandeepan
• Is Part Of: European journal of organic chemistry. Issue 37(2021)
• Page Start: 5312
• Page End: 5319
• Publication Date: 2021-10-06
• Subjects: Electrochemistry -- Electron transfer -- Lanthanides -- Radical reactions -- Reaction mechanism; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202100962
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Samarium diiodide (SmI2 ) is a versatile single electron transfer (SET) reagent in organic synthesis. The advantages of SmI2 arise from various additive induced tailoring of reactions to obtain the desired products in a stereoselective fashion. In most instances, this reagent is used in stoichiometric amount, and this poses a significant environmental issue limiting a broader applicability of SmI2 . Despite challenges in the developments of catalytic methods, recent studies have paved the way for catalytic strategies rejuvenating the applications of SmI2 in synthetic organic chemistry. This review aims to summarize different methods that are used to develop catalytic reactions of SmI2 . A comparison of different approaches and future outlook of this field are discussed. Abstract : SmI2, popularly known as Kagan's reagent, remains at the heart of synthetic reductive chemistry due to its unique versatility. While in most instances this reagent is used as a stoichiometric reagent, recent days have witnessed several methods using catalytic amounts of SmI2 . This review systematically summarizes different methods in developing SmI2 catalyzed reactions. Current challenges and possible future directions are also presented.