Autoimmune pulmonary alveolar proteinosis with a history of vaping and vitamin E‐positive bronchoalveolar lavage. Issue 11 (18th October 2021)

• Record Type: Journal Article
• Authors: Chua, Tzy Harn; Takano, Angela; Yao, Yi Ju; Chow, Sau Yee; Devanand, Anantham; Tay, Chee Kiang
• Is Part Of: Respirology case reports. Volume 9:Issue 11(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-10-18
• Subjects: autoimmune -- pulmonary alveolar proteinosis -- vaping -- vitamin E -- vitamin E acetate; Respiratory organs -- Diseases -- Periodicals; 616.2005
• DOI: 10.1002/rcr2.864
• Languages: English
• ISSNs: 2051-3380

Abstract

Abstract: Pulmonary alveolar proteinosis (PAP) can be due to primary autoimmune and secondary causes, including e‐cigarette, or vaping, product use‐associated lung injury. We present a 33‐year‐old male presenting with PAP and a history of vaping. Serum anti‐granulocyte‐macrophage colony‐stimulating factor antibodies were present. Vitamin E (VE), but not VE acetate, was detected in bronchoalveolar lavage. This is the first report of potential association between vaping and autoimmune PAP. Abstract : We present a 33‐year‐old male presenting with pulmonary alveolar proteinosis (PAP) and a history of vaping. Serum anti‐granulocyte‐macrophage colony‐stimulating factor antibodies were present. Vitamin E (VE), but not VE acetate, was detected in bronchoalveolar lavage. This is the first report of potential association between vaping and autoimmune PAP.