A novel combined dynamic ensemble selection model for imbalanced data to detect COVID-19 from complete blood count. (November 2021)

• Record Type: Journal Article
• Authors: Wu, Jiachao; Shen, Jiang; Xu, Man; Shao, Minglai
• Is Part Of: Computer methods and programs in biomedicine. Volume 211(2021)
• Publication Date: 2021-11
• Subjects: COVID-19 screening -- Imbalanced data -- Dynamic ensemble selection -- Hybrid multiple clustering and bagging -- Candidate classifier generation; Medicine -- Computer programs -- Periodicals; Biology -- Computer programs -- Periodicals; Computers -- Periodicals; Medicine -- Periodicals; Médecine -- Logiciels -- Périodiques; Biologie -- Logiciels -- Périodiques; Biology -- Computer programs; Medicine -- Computer programs; Periodicals; Electronic journals; 610.28
• DOI: 10.1016/j.cmpb.2021.106444
• Languages: English
• ISSNs: 0169-2607

Abstract

Highlights: A combined dynamic ensemble selection (DES) method is proposed for imbalanced data. The combined DES method is applied to detect COVID-19 from complete blood count. Use SMOTE-ENN to balance data and remove noise. Hybrid multiple clustering and bagging to generate cadidate classifiers for DES. Proposed combined DES method outperforms some advanced algorithms. Abstract: Background: As blood testing is radiation-free, low-cost and simple to operate, some researchers use machine learning to detect COVID-19 from blood test data. However, few studies take into consideration the imbalanced data distribution, which can impair the performance of a classifier. Method: A novel combined dynamic ensemble selection (DES) method is proposed for imbalanced data to detect COVID-19 from complete blood count. This method combines data preprocessing and improved DES. Firstly, we use the hybrid synthetic minority over-sampling technique and edited nearest neighbor (SMOTE-ENN) to balance data and remove noise. Secondly, in order to improve the performance of DES, a novel hybrid multiple clustering and bagging classifier generation (HMCBCG) method is proposed to reinforce the diversity and local regional competence of candidate classifiers. Results: The experimental results based on three popular DES methods show that the performance of HMCBCG is better than only use bagging. HMCBCG+KNE obtains the best performance for COVID-19 screening with 99.81% accuracy, 99.86% F1, 99.78% G-mean and 99.81% AUC. Conclusion: Compared to other advanced methods, our combined DES model can improve accuracy, G-mean, F1 and AUC of COVID-19 screening.