Front Cover: Regioselective Synthesis of Fullerene Tris‐adducts for the Preparation of Clickable Fullerene [3 : 3]‐Hexa‐adduct Scaffolds/Regioselective Preparation of Fullerene Bis‐adducts from Cleavable Macrocyclic Bis‐malonates (Eur. J. Org. Chem. 27/2021). Issue 27 (26th June 2021)

• Record Type: Journal Article
• Authors: Trinh, Thi Minh Nguyet; Schillinger, Franck; Guerra, Sebastiano; Meichsner, Eric; Nierengarten, Iwona; Hahn, Uwe; Holler, Michel; Nierengarten, Jean‐François
• Is Part Of: European journal of organic chemistry. Issue 27(2021)
• Page Start: 3768
• Page End: 3768
• Publication Date: 2021-06-26
• Subjects: Bingel reaction -- Fullerene -- Macrocycle -- Regiochemistry -- Silyl protecting groups; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202100730
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The Front Cover shows a 3D‐chess board illustrating strategies developed to introduce several addends onto the fullerene core in a regioselective manner. Di‐ tert ‐butylsilylene‐tethered macrocyclic bis‐ and tris‐malonates have been used to functionalize C60 in multiple Bingel cyclopropanations. The bridging di‐ tert ‐butylsilylene unit is not only a directing group for the cyclization step, it is also a protecting group that can be readily cleaved to afford valuable acyclic fullerene building blocks. These have been used to generate a clickable fullerene [3:3]‐hexa‐adduct scaffold allowing the successive introduction of two azide reagents. More information can be found in the Full Paper and in the Full Paper by J.‐F. Nierengarten et al.