Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure. (October 2021)

• Record Type: Journal Article
• Authors: Segala, Francesco Vladimiro; Sgalla, Giacomo; Salvati, Federica; Berardini, Ludovica; Negri, Marcantonio; Nardella, Elisabetta; Potenza, Annalisa; Murri, Rita; Fantoni, Massimo
• Is Part Of: Respiratory medicine. Volume 187(2021)
• Publication Date: 2021-10
• Subjects: Corticosteroids. COVID-19. organizing pneumonia; Chest -- Diseases -- Periodicals; Chest -- Diseases -- Great Britain -- Periodicals; Respiratory organs -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Appareil respiratoire -- Maladies -- Périodiques; Thorax -- Maladies -- Périodiques; Appareil respiratoire -- Maladies -- Traitement -- Périodiques; Electronic journals; 616.2
• DOI: 10.1016/j.rmed.2021.106571
• Languages: English
• ISSNs: 0954-6111

Abstract

Abstract: Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.