Seroepidemiology of SARS-CoV-2 infections in an urban population-based cohort in León, Nicaragua. (20th October 2021)

• Record Type: Journal Article
• Authors: González, Fredman; Vielot, Nadja A.; Sciaudone, Michael; Toval-Ruíz, Christian; Premkumar, Lakshmanane; Gutierrez, Lester; Cuadra, Edwing Centeno; Munguia, Nancy; Blandón, Patricia; de Silva, Aravinda M.; Rubinstein, Rebecca; Bowman, Natalie; Becker-Dreps, Sylvia; Bucardo, Filemon
• Is Part Of: Epidemiology and infection. Volume 149(2021)
• Publication Date: 2021-10-20
• Subjects: COVID-19 -- epidemiology -- Nicaragua -- SARS-CoV-2 -- seroprevalence; Communicable diseases -- Periodicals; Epidemiology -- Periodicals; 614.4
• DOI: 10.1017/S0950268821002144
• Languages: English
• ISSNs: 0950-2688

Abstract

Abstract: In a Nicaraguan population-based cohort, SARS-CoV-2 seroprevalence reached 28% in the first 6 months of the country's epidemic and reached 35% 6 months later. Immune waning was uncommon. Individuals with a seropositive household member were over three times as likely to be seropositive themselves, suggesting the importance of household transmission.