Comparative bone tissue integration of nanostructured and microroughened dental implants. (March 2015)

• Record Type: Journal Article
• Authors: Salou, Laëtitia; Hoornaert, Alain; Stanovici, Julien; Briand, Sylvain; Louarn, Guy; Layrolle, Pierre
• Is Part Of: Nanomedicine. Volume 10:Number 5(2015)
• Page Start: 741
• Page End: 751
• Publication Date: 2015-03
• Subjects: bone-to-implant contact -- dental implant -- nanostructure -- osseointegration -- titanium; Nanotechnology -- Periodicals; Medical technology -- Periodicals; Nanotechnology -- Therapeutic use -- Periodicals; 610.28
• DOI: 10.2217/nnm.14.223
• Languages: English
• ISSNs: 1743-5889

Abstract

Aim: The aim was to compare osteointegration of nanostructured implants to a microsurface widely used for titanium dental implants.Materials & methods: Commercial titanium dental implants with smooth or microroughened surfaces were nanostructured. Implants were inserted into the femoral condyles of rabbits. After 2 and 4 weeks, histomorphometry calculation was performed.Results: Nanotubes measuring 60 nm in diameter were observed on both S-NANO (roughness: 0.05 μm) and R-NANO (roughness: 0.40 μm) surfaces. The MICRO surface exhibited typical random cavities (roughness: 2.09 μm). At 4 weeks, bone-to-implant contact values were significantly higher for the R-NANO than for the MICRO surface while no differences were observed at 2 weeks.Conclusion: Overall, this study shows that the nanostructured surfaces improved osteointegration similar or higher than the MICRO.