THU0466 EARLY DIAGNOSIS IS ASSOCIATED WITH LESS DISEASE SEVERITY AND BETTER OUTCOME IN FIBROMYALGIA SYNDROME: A TRICENTRIC PROSPECTIVE ANALYSIS OF A COHORT OF 370 PATIENTS. (2nd June 2020)

• Record Type: Journal Article
• Authors: Moshrif, A.; Gouda, W.; Abu-Zaid, M. H.
• Is Part Of: Annals of the rheumatic diseases. Volume 79(2020)Supplement 1
• Page Start: 470
• Page End: 470
• Publication Date: 2020-06-02
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2020-eular.5504
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Delayed diagnosis of fibromyalgia (FM) has been reported to be associated with more economic burden, healthcare utilization and worse response to treatment 1, 2 . However, its impact on the patients' symptomatology and disease severity is still underestimated. Objectives: to evaluate the effect of diagnostic delay (DD) on FM severity and disease assessment parameters. Methods: in this cross sectional study, 370 FM patients were prospectively interviewed. Information about DD, widespread pain index (WPI), symptom severity scale (SSS), total severity scale (SSS+WPI) and number of tender points were collected. We proposed to classify our patients into 3 categories; early diagnosis (ED ≤ 2 years; 83 patients), late diagnosis (LD: >2-7 years; 198) and very late diagnosis (VLD >7 years; 89 patients). Results: the mean age of patients was 33.9 (±9.8) and 79.4 % were female. The mean for DD was 5.6 (±3.6) while the means for SSS, total scale and tender points were 7.8 (±1.6), 16.46 (±4.1), 14.31 (±2.3) respectively. A significant correlation has been found for DD with SSS (r = 0.14), total scale (r = 0.37) and tender points (r = 0.16) but not with WPI (r = 0.059). Comparing the three categories, the mean for SSS was 7.54 (±1.6), 7.73 (±1.4) and 8.25 (±1.7) in the groups of ED, LD and VLD respectively (P =0.008) while the mean for the total scale was 15 (±3.8), 15.95 (±3.8) and 18.96 (±4.4) respectively (P = 0.000) and the mean for tender points was 13.7 (±2.3), 14.35 (±2.1) and 14.77 (±2.8) respectively (P = 0.011). The mean for WPI did not significantly differ as it was 7.45 (±2.8), 7.8 (±3.6) and 7.18 (±4.8) in the groups of ED, LD and VLD respectively (P = 0.415). Conclusion: early diagnosis of FM is associated with low SSS, total severity scale and tender points reflecting a better outcome and a less disease severity. References: [1]Hughes G, Martinez C, Myon E, Taïeb C, Wessely S: The impact of a diagnosis of fibromyalgia on health care resource use by primary care patients in the UK: an observational study based on clinical practice.Arthritis Rheum 2006, 54(1):177-83. [2]Choy et al., A patient survey of the impact of fibromyalgia and the journey to diagnosis BMC Health Services Research 2010, 10:102. Disclosure of Interests: None declared