Recent progress in materials development and biological properties of GTR membranes for periodontal regeneration. (11th October 2021)

• Record Type: Journal Article
• Authors: Ul Hassan, Sadaf; Bilal, Bushra; Nazir, Muhammad Shahid; Naqvi, Syed Ali Raza; Ali, Zufiqar; Nadeem, Sohail; Muhammad, Nawshad; Palvasha, Bushra Anees; Mohyuddin, Aysha
• Is Part Of: Chemical biology & drug design. Volume 98:Number 6(2021)
• Page Start: 1007
• Page End: 1024
• Publication Date: 2021-10-11
• Subjects: antimicrobial properties -- bone tissue regeneration -- GTR membrane -- nanomaterials -- periodontitis; Drugs -- Design -- Periodicals; Pharmaceutical chemistry -- Periodicals; Biochemistry -- Periodicals; 615.19005
• DOI: 10.1111/cbdd.13959
• Languages: English
• ISSNs: 1747-0277

Abstract

Abstract: Chronic periodontal is a very common infection that instigates the destruction of oral tissue, and for its treatment, it is necessary to minimize the infection and the defects regeneration. Periodontium consists of four types of tissues: (a) cementum, (b) periodontal ligament, (c) gingiva, and 4) alveolar bone. In separated cavities, regenerative process also allows various cell proliferations. Guided tissue regeneration (GTR) is a potential procedure that favors periodontal regrowth; however, some limitations (such as ineffective hemostatic property, poor mechanical property, and improper biodegradation) are also associated with it. This review mainly emphasizes on the following areas: (a) a summarized overview of the periodontium and its immunological situations, (b) recently utilized treatments for regeneration of distinctive periodontal tissues; (c) an overview of GTR membranes available commercially, and the latest developments on the characterization and processing of GTR membrane material; and 4) the function of the different non‐polymeric/polymeric materials, which are acting as drug carriers, antibacterial agents, nanoparticles, and periodontal barrier membranes to prevent periodontal inflammation and to improve the strength of the GTR membrane. Abstract : Chronic periodontal is a very common infection that instigates destruction of oral tissue, and for its treatment, it is necessary to minimize the infection and the defects regeneration. This review will focus on guided tissue regeneration technique, its development and future prospects.