Idiopathic desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy: A case report. (2021)

• Record Type: Journal Article
• Authors: Ishimoto, Hiroshi; Sakamoto, Noriho; Ozasa, Mutsumi; Tsutsui, Shin; Hara, Atsuko; Kido, Takashi; Yamaguchi, Hiroyuki; Yamamoto, Kazuko; Obase, Yasushi; Ishimatsu, Yuji; Mukae, Hiroshi
• Is Part Of: Respiratory medicine case reports. Volume 34(2021)
• Publication Date: 2021
• Subjects: Transbronchial lung cryobiopsy -- Desquamative interstitial pneumonia -- Multidisciplinary discussion; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2021.101523
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: A 60-year-old Japanese man with a history of heavy smoking came to our hospital for a detailed examination, suspecting interstitial pneumonia because of gradually increasing dyspnea on exertion over a period of one year. Chest high-resolution computed tomography revealed ground-glass shadows with emphysematous changes. Pathological analysis of samples obtained using transbronchial lung cryobiopsy revealed an accumulation of alveolar macrophages with abundant eosinophilic cytoplasm in the alveolar space. Following a multidisciplinary discussion, the patient was diagnosed with desquamative interstitial pneumonia. To our knowledge, this is the first detailed report of desquamative interstitial pneumonia diagnosed using transbronchial lung cryobiopsy.