Combination treatment with antibiotics and surgical lung resection for Mycobacterium abscessus pulmonary infection in a breast cancer patient. (2021)

• Record Type: Journal Article
• Authors: Tokuyasu, Hirokazu; Makino, Yoshinari; Kubouchi, Yasuaki; Miwa, Ken; Miura, Hiroshi; Ishikawa, Soichiro; Sakai, Hiromitsu; Yamasaki, Akira
• Is Part Of: Respiratory medicine case reports. Volume 34(2021)
• Publication Date: 2021
• Subjects: Antibiotics -- Anticancer chemotherapy -- Breast cancer -- Mycobacterium abscessus -- Surgical lung resection; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2021.101506
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: A 51-year-old woman was admitted to our hospital because of pneumonia after chemotherapy with doxorubicin and cyclophosphamide for left breast cancer. The patient was diagnosed with Mycobacterium abscessus pulmonary infection by the detection of M. abscessus complex (MABC) in sputum cultures. However, MABC is intrinsically resistant to most of the antibacterial agents, and MABC pulmonary disease outcomes with modern antibiotic treatment are currently the worst among all mycobacterial species. We herein report the successful treatment of M. abscessus pulmonary infection by a combination treatment with antibiotics and surgical lung resection.