Theophrastus Bombastus Von Hohenheim (Paracelsus) (1493–1541): The eminent physician and pioneer of toxicology. (2021)

• Record Type: Journal Article
• Authors: Michaleas, Spyros N.; Laios, Konstantinos; Tsoucalas, Gregory; Androutsos, Georges
• Is Part Of: Toxicology reports. Volume 8(2021)
• Page Start: 411
• Page End: 414
• Publication Date: 2021
• Subjects: Paracelsus -- History of toxicology -- Medicine -- Alchemy -- Toxicity -- Mercury -- Chemistry; Toxicology -- Periodicals; Clinical toxicology -- Periodicals; Drug-Related Side Effects and Adverse Reactions; Hazardous Substances; Poisoning; Toxicology; Electronic journals; Periodicals; Periodicals; 571.9505
• DOI: 10.1016/j.toxrep.2021.02.012
• Languages: English
• ISSNs: 2214-7500

Abstract

Graphical abstract: Highlights: Paracelsus introduced the use of chemical substances, such as minerals, into medicine. Paracelsus theorized the constitution of matter based on three elements: sulphur, salt and mercury. Paracelsus emphasized the importance of dosing in distinguishing between toxicity and treatment. Abstract: Theophrastus Bombastus Von Hohenheim known as Paracelsus was a German-Swiss homo universalis, or Renaissance man, whose interests included medicine, chemistry and toxicology. Characterized as a rebellious and great reformer of established medicine of his era, Paracelsus preferred observing nature, over studying ancient texts to find appropriate treatments for various diseases. He also used unconventional curative methods, such as minerals and other inorganic substances, which caused much controversy among his contemporaries. The main purpose of this article is to highlight his contribution on toxicology and the use of mercury.