Cobalt-catalyzed coupling reactions of 2-halobenzamides with alkynes: investigation of ligand-controlled dual pathways. Issue 22 (5th October 2021)

• Record Type: Journal Article
• Authors: Thorat, Vijaykumar H.; Aman, Hasil; Tsai, Yu-Lin; Pallikonda, Gangaram; Chuang, Gary Jing; Hsieh, Jen-Chieh
• Is Part Of: Organic chemistry frontiers. Volume 8:Issue 22(2021)
• Page Start: 6419
• Page End: 6426
• Publication Date: 2021-10-05
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d1qo01402a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : The Co-catalyzed reactions of 2-halobenzamides and alkynes to form quinolinones or 2-vinyl benzamides are described here. These two reactions can be controlled merely by ligands. Abstract : The Co-catalyzed reactions of 2-halobenzamides and alkynes to form isoquinolones or 2-vinyl benzamides are described here. The formation of the two selective products can be fully controlled by adopted ligands. A study of the mechanism demonstrated that these two reactions proceed through different pathways. The radical process and the two-electron transfer activation of the C–X bond are respectively proposed for these two reactions.