Highly efficient Ru(ii)–alkylidene based Hoveyda–Grubbs catalysts for ring-closing metathesis reactions. Issue 60 (24th November 2021)

• Record Type: Journal Article
• Authors: Al-Enezi, Mariam Y.; John, Elizabeth; Ibrahim, Yehia A.; Al-Awadi, Nouria A.
• Is Part Of: RSC advances. Volume 11:Issue 60(2021)
• Page Start: 37866
• Page End: 37876
• Publication Date: 2021-11-24
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d1ra07428h
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Three novel phosphine-free Ru-alkylidenes (7a–7c ) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Abstract : Three novel phosphine-free Ru-alkylidenes (7a–7c ) have been synthesized and utilized as efficient catalysts for ring closing metathesis (RCM) reaction. Spectroscopic data, i.e. NMR and HRMS, along with single crystal X-ray diffraction analysis, were used to confirm their chemical structures. The tosylated carbenoid 7b showed the highest efficiency in cyclizing different acyclic diene substrates. RCM of various (un)substituted N, N -diallylaniline derivatives and stereoselective RCM of different macromolecular dienes were well tolerated using only a catalytic amount (0.5–2.0 mol%) of the additive catalyst (7b ) as compared to the well-known Grubbs (II) and Hoveyda–Grubbs (II) catalysts.