Classics never get old: neurotransmitters shape human cortical interneuron migration. (9th November 2021)

• Record Type: Journal Article
• Authors: Bonafina, Antonela; Javier‐Torrent, Míriam; Nguyen, Laurent
• Is Part Of: EMBO journal. Volume 40:Number 23(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-11-09
• Subjects: Molecular biology -- Periodicals; 572.805
• DOI: 10.15252/embj.2021109935
• Languages: English
• ISSNs: 0261-4189

Abstract

Abstract : While key developmental functions of neurotransmitters have been described in rodent neural progenitors, there is a lack of understanding of their roles in the human fetal brain. A new study published in The EMBO Journal demonstrates that human cortical interneurons that are moving in fused brain organoids express a large repertoire of neurotransmitter receptors whose activation fine tunes selective migration strategies. Abstract : Human cortical interneurons express a large repertoire of neurotransmitter receptors whose activation fine tunes selective migration strategies.