Electrochemically enabled rhodium-catalyzed [4 + 2] annulations of arenes with alkynes. Issue 23 (28th October 2021)

• Record Type: Journal Article
• Authors: Wang, Zi-Chen; Li, Rui-Tao; Ma, Qiang; Chen, Jia-Yi; Ni, Shao-Fei; Li, Ming; Wen, Li-Rong; Zhang, Lin-Bao
• Is Part Of: Green chemistry. Volume 23:Issue 23(2021)
• Page Start: 9515
• Page End: 9522
• Publication Date: 2021-10-28
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d1gc03187b
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : Herein, electrochemically driven, Rh(iii )-catalyzed regioselective annulations of arenes with alkynes have been established. Abstract : Herein, electrochemically driven, Rh(iii )-catalyzed regioselective annulations of arenes with alkynes have been established. The strategy, combining the use of a rhodium catalyst with electricity, not only avoids the need for using a stoichiometric amount of external oxidant, but also ensures that the transformations proceed under mild and green conditions, which enable broad functional group compatibility with a variety of substrates, including drugs and pharmaceutical motifs. Moreover, the electrolysis reaction was made operationally simple by employing an undivided cell, and proceeds efficiently in aqueous solution in air.