Automated glycan assembly of peptidoglycan backbone fragments. Issue 45 (4th November 2021)

• Record Type: Journal Article
• Authors: Dallabernardina, Pietro; Benazzi, Valentina; Laman, Jon D.; Seeberger, Peter H.; Loeffler, Felix F.
• Is Part Of: Organic & biomolecular chemistry. Volume 19:Issue 45(2021)
• Page Start: 9829
• Page End: 9832
• Publication Date: 2021-11-04
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/d1ob01987b
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : The automated glycan assembly of different oligosaccharide fragments of the bacterial peptidoglycan backbone is reported. Abstract : We report the automated glycan assembly (AGA) of different oligosaccharide fragments of the bacterial peptidoglycan (PGN) backbone. Iterative addition on a solid support of an acetyl glucosamine and a new muramic acid building block is followed by cleavage from the solid support and final deprotection providing 10 oligosaccharides up to six units.