AB1001 ARE ANY DIFFERENCES IN THE LOCATION OF BONE LESIONS BETWEEN BONE MALIGNANT TUMORS AND INFLAMMATORY OSTEOPATHIES?. (June 2019)

• Record Type: Journal Article
• Authors: Silkov, Vyacheslav; Suvorov, Nikita; Kostik, Mikhail; Kopchak, Olga; Maletin, Alexei; Zorin, Vyacheslav; Mushkin, Alexander
• Is Part Of: Annals of the rheumatic diseases. Volume 78(2019)Supplement 2
• Page Start: 1967
• Page End: 1967
• Publication Date: 2019-06
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2019-eular.7898
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Different pediatric bone destructive diseases may have similar radiological findings but have their typical localizations [1]. Objectives: The aim of our study was to differences in the bone lesions location in various pediatric bone destructive diseases. Methods: Our cohort (n=204) consists of four main subtypes: i) chronic non-bacterial osteomyelitis (CNO, n=91), ii) hematogenous osteomyelitis (HO, n=47); iii) tuberculosis osteomyelitis (TBO, n=33), and iv) malignant bone tumors (MBT, n=33) - osteosarcoma and Ewing's sarcoma. Results: Al bone destructive diseases have the similar frequency of femur and humerus involvement. MBT patients compare to others had the highest onset age, and higher frequency of pelvic involvent, and comparatively rare the involvement of spine, tibia, foot bones, sternum, the bones of forearm and hand (table). Conclusion: Patients with bone destructive process with femur, humerus and pelvic involvement have to be under high level of consideration about all type of osteopathy, especially MBT. This work supported by the Russian Foundation for Basic Research (grant ? 18-515-57001). References: [1] McCarville MB. The child with bone pain: malignancies and mimickers. Cancer Imaging. 2009;9 Spec No A:S115-21. Disclosure of Interests: None declared