O-diphenoloxidase concentrations in leprosy. Issue 6195 (13th October 1979)

• Record Type: Journal Article
• Authors: Reza, K; Talib, S; Imam, S K
• Is Part Of: BMJ. Volume 2:Issue 6195(1979)
• Page Start: 900
• Page End: 901
• Publication Date: 1979-10-13
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.2.6195.900
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : O-diphenoloxidase activity was studied in 15 patients with lepromatous leprosy, 15 with tuberculois leprosy, and 15 controls. O-diphenoloxidase isolated from skin and serum samples of patients with lepromatous leprosy had the specificity of a bacterially derived enzyme and not that of a mammalian-derived enzyme. Only the patients who had lepromatous leprosy for over two years showed enzyme activity in serum, though all showed it in skin tissue. O-diphenoloxidase activity in serum may be a useful diagnostic marker of lepromatous leprosy.