AB0951 Ultrasonographic assessment of nail in psoriatic disease found a link between nail disorder and soft tissue swelling around the nail. (12th June 2018)

• Record Type: Journal Article
• Authors: Okano, T.; Inui, K.; Yamada, Y.; Mandai, K.; Mamoto, K.; Sugioka, Y.; Koike, T.; Nakamura, H.
• Is Part Of: Annals of the rheumatic diseases. Volume 77(2018)Supplement 2
• Page Start: 1600
• Page End: 1601
• Publication Date: 2018-06-12
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2018-eular.2895
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Although skin lesion is the most typical findings in patients with psoriasis (PsO), nail psoriasis is also one of the clinical manifestation. Moreover, nail disorders in PsO are known as a risk factor for psoriatic arthritis (PsA). However, pathological feature and the relationship with inflammation of the soft tissue around the nail is unknown. 1–2 Objectives: The aim of this study was to compare the soft tissue thickness around the nail in patients with PsO, PsA and other rheumatic diseases by using ultrasonography. Methods: Twenty-five PsO · 35 PsA · 23 rheumatoid arthritis (RA) · 28 ulcerative colitis (UC) and 13 Crohn's disease (CD) patients performed ultrasonographic assessment in nail were included in this analysis. Ultrasonographic examination was performed by using HI VISION Ascendus (Hitachi Medical Corporation, Japan) with a multifrequency linear transducer (18–6 MHz) and the grey scale (GS) and power Doppler (PD) findings were assessed. The distance between the proximal nail fold on the dorsal side of the nail matrix and the nail bed on the volar side of the nail matrix was measured by electric calliper Results: The distance between the proximal nail fold and the nail bed was 2.58±0.56 mm in PsA and 2.55±0.58 mm in PsO patients (p=0.603). Among the 60 patients who combined PsO and PsA patients, 41 patients with nail psoriasis and 19 patients without nail psoriasis was compared. The distance was 2.68±0.62 mm in patients with nail psoriasis and 2.30±0.41 mm in without nail psoriasis (p<0.001), which was also swelling compared with the RA, UC and CD group. Conclusions: Soft tissue thickness around the nail in patients with PsO and PsA was compared with other rheumatic diseases by ultrasonographic assessment. In patients with PsO and PsA with nail psoriasis, soft tissue swelling around nail was observed. References: [1] Sandobal C, Carbó E, Iribas J, et al. Ultrasound nail imaging on patients with psoriasis and psoriatic arthritis compared with rheumatoid arthritis and control subjects. J Clin Rheumatol. 2014;20:21–4. [2] Aydin SZ, Castillo-Gallego C, Ash ZR, et al. Ultrasonographic assessment of nail in psoriatic disease shows a link between onychopathy and distal interphalangeal joint extensor tendon enthesopathy. Dermatology. 2012;225:231–5. Acknowledgements: We wish to thank Tomoko Nakatsuka for clinical assistant, Setsuko Takeda, Emi Yamashita and Yuko Yoshida for their special efforts as a sonographer and collecting data. Disclosure of Interest: None declared