PREDIABETES IN NAÏVE GREEK HYPERTENSIVE PATIENTS. (April 2021)

• Record Type: Journal Article
• Authors: Papadakis, J.A.; Papanikolaou, K.; Theodorakopoulou, V.; Papakitsou, I.; Psicharaki, F.; Vrentzos, G.
• Is Part Of: Journal of hypertension. Volume 39(2021)e-Supplement 1
• Publication Date: 2021-04
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000746804.70965.8f
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: Prediabetes subjects have increased risk for diabetes and cardiovascular disease. Aim of our study was to find the incidence of prediabetes, in naive hypertensives in Greece. Design and method: We studied 688 [304 (44.2%) were men] hypertensives, who were under neither antihypertensive nor lipid-lowering medications, and they were not diabetics. Their median age was 55 (range: 15–82) years. Prediabetes was defined by ADA criteria (fasting glucose: 100–125 mg/dl). Results: Two hundred forty five out of 688 patients (35.6%) met the criteria for prediabetes. It was more prevalent in males than in females (42.4% vs 30.2%, p = 0.001). On the contrary, there was no statistically significant difference in the age between the 2 groups. Subjects with prediabetes had significantly higher body mass index (BMI) (31.5 + 5.8 vs 30.3 + 5.0; p = 0.01) when compared with the rest hypertensives. Hypertensives with prediabetes had significantly higher systolic blood pressure (SBP) levels than the others (158.4 + 18.5 vs 155.2 + 18.6; p < 0.05), while there was no significant difference in diastolic blood pressure levels (95.0 + 11.0 vs 94.7 + 11.3; p = 0.70) between the 2 groups. There was no significant difference in total, high density, and low density cholesterol and triglycerides serum levels between the two groups. On the contrary hypertensives with prediabetes had significantly increased all liver functional tests than those without. Conclusions: Our results suggest that more than one third of naive hypertensives had prediabetes. These subjects had higher SBP levels and they were more obese. They had also increased liver functional tests, without any difference in their lipid profile.