SAT0148 Fibromyalgia syndrome characterised by patient-reported sleep, fatigue, mood and quality of life. (1st June 2001)

• Record Type: Journal Article
• Authors: Sesti, AM; Corbin, AE; McLaughlin-Miley, C; Jaffe, M; Moore, J; Young, JP; LaMoreaux, L; Sharma, U; Versavel, M
• Is Part Of: Annals of the rheumatic diseases. Volume 60(2001)Supplement 1
• Page Start: A240
• Page End: A240
• Publication Date: 2001-06-01
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2001.607
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Fibromyalgia (FM) is a chronic condition of pain, tender points and multiple associated symptoms. A diagnosis is made by the ACR 1990 criteria requiring a history of widespread pain and pain in 11 of 18 tender points. Although pain is required for a diagnosis, the associated symptoms contribute to the syndromatic nature of the condition. This trial included measures of sleep, fatigue, mood, QoL and pain. Objectives: Methods: 529 fibromyalgia patients per ACR criteria were assessed at baseline after discontinuing meds used for FM pain/insomnia (e.g. antidepressants, sedatives). The questionnaires were the Medical Outcomes Study Sleep Scale (MOS-SS), Multidimensional Assessment of Fatigue (MAF), Hospital Anxiety and Depression Scale (HADS) and SF-36. The MOS-SS has 12-items with an index score and 7 subscales: disturbance, snoring, awakening short of breath/headache (SOB/HA), adequacy, somnolence (range 0–100); quantity of sleep (reported hours); and, optimal sleep (% with 7–8 h). Higher scores on the MOS-SS indicate more of the measured domain. The MAF has 16 items and 1 global index score from items measuring severity, distress, impact on activities and frequency of fatigue (range 1–50). The HADS has 14-items for anxiety/depression ranging from 0–21. Higher MAF and HADS scores indicate greater impairment. The SF-36 has 8 subscales measuring general health status with higher scores indicating better health states. Results: Demographics and pain scores are reported in the companion abstract by Corbin, et al . 2001. Baseline MOS-SS were: overall problems (62.3), disturbance (62.5), snoring (36.9), SOB/HA (36.1), adequacy (19.7), somnolence (49.5), quantity (5.6), and 21.7% reported optimal sleep. The fatigue index was 38.9 and the HADS scores were mild with anxiety (10.1) and depression (8.6). SF-36 scores were physical function (40.5), role physical (15.2), bodily pain (27.6), general health (47.5), vitality (20.4), social functioning (48.8), role-emotional (46.0) and mental health (58.7). Conclusion: These data suggest that FM patients have impaired sleep and concomitant fatigue based on relatively high index scores. The predominant sleep problems were disrupted and inadequate sleep with a fair amount of somnolence. Patients reported low quality of life, particularly on domains of bodily pain, role physical, and vitality. Along with a high level of pain, impairments in sleep, fatigue and QoL were reported in this FM population.