397A Meta-Analysis of Randomized Clinical Trials on Calcium Intake for Obesity Indices. (2nd September 2021)

• Record Type: Journal Article
• Authors: Hong, Jee Yeon; Lee, Ji Seon; Woo, Hye Won; Om, Ae Son; Kim, Mi Kyung
• Is Part Of: International journal of epidemiology. Volume 50(2021)Supplement 1
• Publication Date: 2021-09-02
• Subjects: Epidemiology -- Periodicals; 614.4
• DOI: 10.1093/ije/dyab168.283
• Languages: English
• ISSNs: 0300-5771

Abstract

Abstract: Background: There was no consistent finding of changes of obesity indices including fat mass by calcium supplements and dairy products intervention. Therefore, we conducted the meta-analysis of evidence on calcium supplements and dairy products (≥ 12 weeks) on changes in the obesity index (fat mass, as well as weight, body mass index, waist circumference) from randomized controlled trials (RCTs). Methods: We searched for original articles during the last 10 years until August 19, 2019, using PubMed and EMBASE. The extracted data were analysed with random effects, inverse variance model using Review Manager 5.3 ver. Results: Finally, ten RCTs with calcium supplements and fourteen RCTs with dairy products among adults aged 18 years old or over were selected. The intervention with calcium supplements showed significant change of fat mass (SMD, 95% CI; -0.21 [-0.37, -0.04], p = 0.02), but not in changes in body weight (p = 0.45), BMI (p = 0.14) and WC (p = 0.88). Dairy products also showed significant results in changes of fat mass (SMD, 95% CI; -0.51 [-0.90, -0.11], p = 0.01) as well as BMI (WMD, 95% CI; -0.46 [-0.67, -0.26], p < 0.00001), but not in changes of body weight (p = 0.70) and WC (p = 0.27). Conclusions: The fat mass may be reduced by both calcium supplements and dairy products intervention over 12 weeks among adults 18 years old or over. Dairy products may be beneficial for BMI reduction. Key messages: Dietary calcium intake might reduce fat mass in adults (≥ 18 years).