Distinguishing Multiple Coding Levels in Theta Band Activity During Working Memory Gating Processes. (1st December 2021)

• Record Type: Journal Article
• Authors: Rempel, Sarah; Colzato, Lorenza; Zhang, Wenxin; Wolff, Nicole; Mückschel, Moritz; Beste, Christian
• Is Part Of: Neuroscience. Volume 478(2021)
• Page Start: 11
• Page End: 23
• Publication Date: 2021-12-01
• Subjects: ERPs event-related potentials -- RIDE residue iteration decomposition -- TBA theta-band activity -- WM working memory; theta-band activity -- cognitive control -- working memory -- working memory gating -- EEG beamforming -- EEG signal decomposition; Neurochemistry -- Periodicals; Neurophysiology -- Periodicals; Neurology -- Periodicals; Neurochimie -- Périodiques; Neurophysiologie -- Périodiques; Neurochemistry; Neurophysiology; Electronic journals; Periodicals; Electronic journals; 612.8
• DOI: 10.1016/j.neuroscience.2021.09.025
• Languages: English
• ISSNs: 0306-4522

Abstract

Highlights: Various information contents are concomitantly coded by theta activity during WM gating. Functional neuroanatomical architecture of these processes is delineated. Conceptual connections are shown between WM and cognitive control regarding information coding in theta activity. Abstract: Cognitive control and working memory (WM) processes are essential for goal-directed behaviour. Cognitive control and WM are probably based on overlapping neurophysiological mechanisms. For example, theta-band activity (TBA) plays an important role in both functions. For cognitive control processes, it is known that different aspects of information about stimulus content, motor processes and stimulus–response relationships are encoded simultaneously in the TBA. All this information is probably processed during WM gating processes and must be controlled during them. However, direct data for this are lacking. This question is investigated in this study by combining methods of EEG temporal signal decomposition, time–frequency decomposition and beamforming. We show that portions of stimulus-related information, motor response-related information and information related to the interaction between the stimulus and motor responses in the TBA are influenced in parallel and to a similar extent by WM gate opening and gate closing processes. Nevertheless, it is stimulus-related information in the theta signal in particular that modulates behavioural performance in WM-gating. The data suggest that the identified processes are implemented in specific neuroanatomical structures. In particular, the medial frontal cortex, temporal cortical regions and insular cortex are involved in these dynamics. The study shows that principles of information coding relevant to cognitive control processes are also crucial for understanding WM gating.