Disconnected Motor Intention and Spatial Attention in a Case of Probable Marchiafava-Bignami Disease. Issue 3 (September 2021)

• Record Type: Journal Article
• Authors: Kobayashi, Shunsuke; Hirose, Masaki; Akutsu, Yukiko; Hirayama, Kazumi; Ishida, Yoshinori; Ugawa, Yoshikazu
• Is Part Of: Cognitive and behavioral neurology. Volume 34:Issue 3(2021)
• Publication Date: 2021-09
• Subjects: crossed hemispatial neglect -- crossed avoiding reaction -- Marchiafava–Bignami disease -- disconnection; Neuropsychiatry -- Periodicals; Clinical neuropsychology -- Periodicals; 616.8005
• DOI: 10.1097/WNN.0000000000000274
• Languages: English
• ISSNs: 1543-3633

Abstract

Abstract : Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism that typically causes demyelination and necrosis of the corpus callosum. Here, we report a man with probable MBD with callosal and right medial paracentral lesions who presented with abnormal reaching behavior and ideomotor apraxia of the left hand. He exhibited difficulty in reaching with the left hand when a target object was placed on his right-hand side, and he exhibited rightward bias when using his right hand in a line bisection task. These disturbances in reaching suggest disruption of the top–down control of motor intention and spatial attention at the corpus callosum. Abstract : Supplemental Digital Content is available in the text.