Bioenergetic Mechanisms Linking V˙O2 Kinetics and Exercise Tolerance. Issue 4 (October 2021)

• Record Type: Journal Article
• Authors: Goulding, Richie P.; Rossiter, Harry B.; Marwood, Simon; Ferguson, Carrie
• Is Part Of: Exercise and sport sciences reviews. Volume 49:Issue 4(2021)
• Publication Date: 2021-10
• Subjects: muscle fatigue -- work efficiency -- power-duration relation -- mitochondria -- inorganic phosphate -- oxidative capacity; Sports -- Physiological aspects -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Sports medicine -- Periodicals; 612.76
• DOI: 10.1249/JES.0000000000000267
• Languages: English
• ISSNs: 0091-6331

Abstract

Abstract : We hypothesize that the V˙O2 time constant (τV˙O2 ) determines exercise tolerance by defining the power output associated with a "critical threshold" of intramuscular metabolite accumulation ( e.g., inorganic phosphate), above which muscle fatigue and work inefficiency are apparent. Thereafter, the V˙O2 "slow component" and its consequences (increased pulmonary, circulatory, and neuromuscular demands) determine performance limits. Abstract : V˙O2 kinetics determine exercise tolerance by mediating the power output at which muscle metabolite accumulation exceeds a "critical threshold."